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Pigmentation concerns are a growing, global issue and affect more than 90 percent of adults over the age of 50. Regardless of skin colour; sun spots, age spots, and melasma are significant issues because of their negative psychological and emotional impact, affecting quality of life and self-confidence. Pigmentation is due to a build up of melanin (the protein in our skin responsible for our skin colour) caused by several factors including UV sunlight exposure, hormones, medications or sometimes after an injury to the skin. In some cases, surgical and acne scarring can also result in an overproduction of melanin and hyperpigmentation of the skin.

Dermamelan is the world’s leading medical and clinically-proven depigmentation treatment. Its unique and innovative formula safely and efficiently removes hyperpigmentation and prevents its reappearance for a long-lasting outcome. It differs from its little sister treatment Cosmelan by being more potent and effective and is only available under the supervision of a medical practitioner.

What to Expect

Dermamelan’s unique medical depigmentation method aims to treat extreme skin hyperpigmentation, reducing the appearance of brown spots, blemishes, and sun damage for a clearer and more even complexion. Its dual action works through an intensive corrective and pigment-regulating action, treating established brown patches through increased cellular turnover whilst also reducing the cellular processes responsible for new pigmentation production.

By working in this synergistic and complementary way, Dermamelan controls the overstimulation of melanin synthesis over a prolonged time to prevent hyperpigmentation from returning. This potent treatment also regulates melasma’s vascular, inflammatory, and hormonal components. It also stimulates the skin’s structural proteins for improved quality, hydration, and firmness.

The active ingredients in Dermamelan include azelaic acid, kojic acid, phytic acid, ascorbic acid, arbutin and titanium dioxide. These agents have a profound brightening effect by reducing the amount of melanin produced and preventing melanin transfer to the skin surface.

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What conditions can be treated with Dermamelan?

The most common pigmentation concerns that can be treated with Dermamelan include:

  • Melasma / Chloasma
  • Brown spots
  • Hyperpigmentation and discoloured spots from acne
  • Post-inflammatory hyperpigmentation
  • Uneven skin tone or brown blotchy skin
  • Hyperpigmentation from laser and peel treatments
  • Rosacea
  • Lentigo

Ideal candidates for Dermamelan

Before conducting a treatment, a consultation at our clinic is essential to assess your suitability, individual concerns, and your goals for the treatment. Our highly-skilled clinicians will evaluate your skin and pigmentation concerns and devise a treatment plan that is right for you.

Generally, Dermamelan can be used by men and women of all skin tones and types who suffer from pigmentation concerns. Although it is designed for patients with severe pigmentation issues, patients with more minor pigmentation or sun damage can still find this treatment hugely beneficial.

However, patients who are currently pregnant/breastfeeding or suffering from very severe cystic acne are unsuitable for Dermamelan.

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Dermamelan procedure

Dermamelan involves two stages of treatment that take 6 to 12 months to complete:

The in-clinic phase
Following a proper diagnosis of your pigmentation concern, your treatment program begins with a chemical peel and home skincare preparation. At your next appointment, a mask that provides the intensive depigmenting action is applied. The patient removes this mask at home after the time indicated by the clinic staff, which can be between 8-12 hours, depending on the severity of a patient’s skin and skin type. The treatment is comfortable and takes only 45 minutes at our clinic. Patients may continue their daily routine afterwards, although some swelling, redness and peeling can be expected.

The at-home phase
This phase involves strict adherence to a home skincare regime for six months using the Dermamelan skin care products, which helps to treat the root of the problem and gain a comprehensive and long-lasting result. This ensures that the maximum results from Dermamelan can be achieved. During this time, you will have regular appointments with our dermal clinician to monitor your skin condition, providing you with an ongoing, personalised skincare routine as prescribed by our clinicians.

What conditions can be treated with Dermamelan?

Dermamelan recovery and aftercare

Immediately following your treatment, your skin will appear reddened and feel a little tight. You will likely experience some swelling, peeling, and sensitivity over the first week or two but typically this will dissipate within two weeks. Applying the Dermamelan home products helps the skin heal and recover faster, as does preparing the skin with the dedicated skin care products prior to the Dermamelan mask application.

Skin peeling, shedding, and dryness are to be expected with this treatment, and you will need to avoid direct sun exposure as your skin peels. The first phase of shedding takes roughly ten days and can be very intense as the skin peels and flakes off. It is crucial that patients do not pull, scratch or tug off the shedding skin and let it flake away on its own to avoid complications.

Once this phase is complete, your skin will appear dry and flakey for about 2-3 weeks, and some redness may also persist. Your pigmentation lesions will become darker as it is pushed towards the skin’s surface and can last until the shedding phase has been completed, where the pigmentation will fall away.

It is vitally important to continue your prescribed skincare regimen which helps the skin to heal and recover during this time. This skincare regime is also essential for long lasting results.

Risks and side effects of Dermamelan

Dermamelan is a minimally invasive topical treatment that does not prevent you from following your daily life. During the initial phase and after applying the Dermamelan treatment mask, the skin may become irritated, swollen or show redness. These symptoms are a normal and expected reaction and will ease within the first two weeks. During the home phase, it is common to experience peeling and sensitivity, which lessen with the application of the recommended home skincare products from the clinic.


When can I see the results of Dermamelan?

The most significant change occurs within a few weeks from applying the mask. You’ll notice an improvement in skin texture and a reduction of hyperpigmentation due to melanin (pigmentation) being removed from the outer layers of the skin. However, you must continue the treatment for the entire six months, as removing the accumulated melanin is not enough. We need to also regulate its overproduction and minimise its reappearance.

Is it a treatment compatible with my daily activities?

Dermamelan is a non-invasive topical treatment and does not prevent you from continuing your usual activities. However, it is vitally important that the daily homecare regime is maintained and sun exposure avoided as much as possible to maximise results.

How many treatments will I need?

For most people, one initial Dermamelan mask followed by the six-month home skincare program will be sufficient. You may need a top up treatment after a month or so if you have very stubborn pigmentation. Depending on the response to the treatment and desired outcome, some patients will opt to have maintenance Dermamelan treatment annually to keep their pigmentation at bay.

Will spots disappear entirely and forever?

Pigmentation spots will be significantly reduced following the treatment, but not every spot may disappear altogether. Occasionally, patients may need a repeat treatment with Dermamelan or a combination with another treatment modality such as laser for improved results. It is essential to follow your prescribed home care routine and to consistently use specific SPF protection to minimise repigmentation.

What is the best time of year to perform the treatment?

Dermamelan can be performed anytime if patients practice adequate sun avoidance and use a high SPF sunscreen.

What are the advantages vs other depigmentation treatments?

Other treatments such as laser or peel have a corrective action on the spots by removing the pigment accumulated in the skin, but their reappearance cannot be avoided. Dermamelan has a dual curative and regulating activity to treat the origin of the problem and maintain pigment overproduction to prevent a recurrence.

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